A Randomised Controlled Trial Comparing Convergent Hybrid Ablation to Catheter Ablation in Patients With Persistent Atrial Fibrillation and Heart Failure
Status: Recruiting
Location: See all (7) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
A randomised controlled trial to assess the efficacy of staged hybrid ablation when compared with standard catheter ablation in patients with non-paroxysmal atrial fibrillation (AF) and Heart Failure
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥ 18 years
• Persistent or Long-standing Persistent AF
• Dilated left atrium (at least moderately dilated)
• Suitable for either procedure
• LVEF \< 50%
Locations
Other Locations
United Kingdom
Ashford & St Peters Hospital NHS Trust
RECRUITING
Chertsey
Epsom General Hospital
RECRUITING
Epsom
Cromwell Hospital
ACTIVE_NOT_RECRUITING
London
Royal Surrey County Hospital
RECRUITING
London
St Anthonys Hospital
ACTIVE_NOT_RECRUITING
London
St Georges at Kingston Hospital
RECRUITING
London
St Georges University of London
RECRUITING
London
Contact Information
Primary
Riyaz A Kaba
rkaba@sgul.ac.uk
020 8725 4571
Backup
Omar Ahmed
m2109536@sgul.ac.uk
020 8725 4571
Time Frame
Start Date: 2022-06-25
Estimated Completion Date: 2027-10
Participants
Target number of participants: 120
Treatments
Experimental: Convergent Hybrid Ablation +/- Left Atrial Appendage Exclusion
Staged Convergent Hybrid Ablation Procedure~Stage 1 - Minimally-Invasive Surgical Epicardial Ablation Procedure +/- concomitant LAA exclusion.~Stage 2 - Endocardial Catheter Ablation
Active_comparator: Standard Endocardial Catheter Ablation
Standard endocardial catheter ablation
Related Therapeutic Areas
Sponsors
Leads: St. George's Hospital, London